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Case Report 


Acute invasive rhinosinusitis case caused by Aspergillus flavus in two patients prediagnosed with mucormycosis

Müge Aslan, Yasemin Oz, Ozcan Bor, Eren Gündüz, Filiz Aksit.


Abstract
Acute invasive rhinosinusitis caused by Aspergillus spp. may lead to invasive disease and mortality, especially in im¬munocompromised individuals. In this report, two invasive fungal rhinosinusitis cases in an immune compromised patient have been presented that were pre-diagnosed with mucormycosis, but with a positive culture for Aspergillus flavus. Twenty-four years old male patient with aplastic anemia and seven years old patient with acute lymphoblastic leukemia; facial pain, edema, and necrotic lesions developed in both cases. Tissue samples were obtained from lesions through the nose by biopsy for definitive diagnosis. Septate fungal hyphae observed on the microscopic examination of the specimen, and A. flavus was isolated in the culture in both cases. Surgical debridement could not be performed because of patients ' general conditions. Despite antifungal therapy and treatments, patients died. Delay in diagnosis and treatment may lead to high mortality rates. These cases emphasize the importance of diagnosis with culture. J Microbiol Infect Dis 2015;5(3): 137-141
Müge Aslan, Yozgat State Hospital, Microbiology Laboratory, Yozgat, Turkey, Acute invasive rhinosinusitis case caused by Aspergillus flavus in two patients prediagnosed with mucormycosis, Müge Aslan, Yozgat State Hospital, Microbiology Laboratory, Yozgat, Turkey J Microbiol Infect Dis 2015;5(3): 137-141


doi: 10.5799/ahinjs.02.2015.03.0193


 
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How to Cite this Article
Pubmed Style

Aslan M, Oz Y, Bor O, Gunduz E, Aksit F. Acute invasive rhinosinusitis case caused by Aspergillus flavus in two patients prediagnosed with mucormycosis. J Microbiol Infect Dis. 2015; 5(3): 137-141 .

doi:10.5799/jmid2015.03.0193

Web Style

Aslan M, Oz Y, Bor O, Gunduz E, Aksit F. Acute invasive rhinosinusitis case caused by Aspergillus flavus in two patients prediagnosed with mucormycosis. https://www.jmidonline.org/?mno=302657316 [Access: June 28, 2026].

doi:10.5799/jmid2015.03.0193

AMA (American Medical Association) Style

Aslan M, Oz Y, Bor O, Gunduz E, Aksit F. Acute invasive rhinosinusitis case caused by Aspergillus flavus in two patients prediagnosed with mucormycosis. J Microbiol Infect Dis. 2015; 5(3): 137-141 .


doi:10.5799/jmid2015.03.0193

Vancouver/ICMJE Style

Aslan M, Oz Y, Bor O, Gunduz E, Aksit F. Acute invasive rhinosinusitis case caused by Aspergillus flavus in two patients prediagnosed with mucormycosis. J Microbiol Infect Dis. (2015), [cited June 28, 2026]; 5(3): 137-141 .


doi:10.5799/jmid2015.03.0193

Harvard Style

Aslan, M., Oz, . Y., Bor, . O., Gunduz, . E. & Aksit, . F. (2015) Acute invasive rhinosinusitis case caused by Aspergillus flavus in two patients prediagnosed with mucormycosis. J Microbiol Infect Dis, 5 (3), 137-141 .


doi:10.5799/jmid2015.03.0193

Turabian Style

Aslan, Muge, Yasemin Oz, Ozcan Bor, Eren Gunduz, and Filiz Aksit. 2015. Acute invasive rhinosinusitis case caused by Aspergillus flavus in two patients prediagnosed with mucormycosis. Journal of Microbiology and Infectious Diseases, 5 (3), 137-141 .


doi:10.5799/jmid2015.03.0193

Chicago Style

Aslan, Muge, Yasemin Oz, Ozcan Bor, Eren Gunduz, and Filiz Aksit. "Acute invasive rhinosinusitis case caused by Aspergillus flavus in two patients prediagnosed with mucormycosis." Journal of Microbiology and Infectious Diseases 5 (2015), 137-141 .


doi:10.5799/jmid2015.03.0193

MLA (The Modern Language Association) Style

Aslan, Muge, Yasemin Oz, Ozcan Bor, Eren Gunduz, and Filiz Aksit. "Acute invasive rhinosinusitis case caused by Aspergillus flavus in two patients prediagnosed with mucormycosis." Journal of Microbiology and Infectious Diseases 5.3 (2015), 137-141 . Print.


doi:10.5799/jmid2015.03.0193

APA (American Psychological Association) Style

Aslan, M., Oz, . Y., Bor, . O., Gunduz, . E. & Aksit, . F. (2015) Acute invasive rhinosinusitis case caused by Aspergillus flavus in two patients prediagnosed with mucormycosis. Journal of Microbiology and Infectious Diseases, 5 (3), 137-141 .


doi:10.5799/jmid2015.03.0193

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