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Case Report 


Disseminated Fusariosis with Secondary Hemophagocytic Lymphohistiocytosis

GARIMA Nirmal, Guruprasad Chellappan Sojamani, Manjusha Nair, Swapna R Nath, Priyakumari Thankamony.


Abstract
We report here a 7-year girl with B-Acute Lymphoblastic Leukemia (ALL) on Berlin Frankfurt Munster (BFM) based induction chemotherapy who presented with fever, cough, and painful necrotic skin lesions simulating pseudomonas sepsis. The patient was eventually diagnosed with disseminated fusariosis. While on combination antifungal therapy, fever reappeared with pancytopenia and hepatosplenomegaly, and she was subsequently diagnosed with secondary Hemophagocytic lymphohistiocytosis (HLH) and was treated using the HLH 2004 protocol. The child responded to treatment well. This report highlights the high index of clinical suspicion, appropriate investigations needed to diagnose fusariosis and secondary HLH in pediatric oncology practice promptly, and the successful treatment outcome despite having them both. J Microbiol Infect Dis 2022; 11(2):69-73.


 
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How to Cite this Article
Pubmed Style

GARIMA Nirmal, Guruprasad Chellappan Sojamani, Manjusha Nair, Swapna R Nath, Priyakumari Thankamony. Disseminated Fusariosis with Secondary Hemophagocytic Lymphohistiocytosis. J Microbiol Infect Dis. 2022; 12(2): 69-73 . doi:10.5799/jmid.1130139


Web Style

GARIMA Nirmal, Guruprasad Chellappan Sojamani, Manjusha Nair, Swapna R Nath, Priyakumari Thankamony. Disseminated Fusariosis with Secondary Hemophagocytic Lymphohistiocytosis. https://www.jmidonline.org/?mno=302657273 [Access: October 13, 2024]. doi:10.5799/jmid.1130139


AMA (American Medical Association) Style

GARIMA Nirmal, Guruprasad Chellappan Sojamani, Manjusha Nair, Swapna R Nath, Priyakumari Thankamony. Disseminated Fusariosis with Secondary Hemophagocytic Lymphohistiocytosis. J Microbiol Infect Dis. 2022; 12(2): 69-73 . doi:10.5799/jmid.1130139



Vancouver/ICMJE Style

GARIMA Nirmal, Guruprasad Chellappan Sojamani, Manjusha Nair, Swapna R Nath, Priyakumari Thankamony. Disseminated Fusariosis with Secondary Hemophagocytic Lymphohistiocytosis. J Microbiol Infect Dis. (2022), [cited October 13, 2024]; 12(2): 69-73 . doi:10.5799/jmid.1130139



Harvard Style

GARIMA Nirmal, Guruprasad Chellappan Sojamani, Manjusha Nair, Swapna R Nath, Priyakumari Thankamony (2022) Disseminated Fusariosis with Secondary Hemophagocytic Lymphohistiocytosis. J Microbiol Infect Dis, 12 (2), 69-73 . doi:10.5799/jmid.1130139



Turabian Style

GARIMA Nirmal, Guruprasad Chellappan Sojamani, Manjusha Nair, Swapna R Nath, Priyakumari Thankamony. 2022. Disseminated Fusariosis with Secondary Hemophagocytic Lymphohistiocytosis. Journal of Microbiology and Infectious Diseases, 12 (2), 69-73 . doi:10.5799/jmid.1130139



Chicago Style

GARIMA Nirmal, Guruprasad Chellappan Sojamani, Manjusha Nair, Swapna R Nath, Priyakumari Thankamony. "Disseminated Fusariosis with Secondary Hemophagocytic Lymphohistiocytosis." Journal of Microbiology and Infectious Diseases 12 (2022), 69-73 . doi:10.5799/jmid.1130139



MLA (The Modern Language Association) Style

GARIMA Nirmal, Guruprasad Chellappan Sojamani, Manjusha Nair, Swapna R Nath, Priyakumari Thankamony. "Disseminated Fusariosis with Secondary Hemophagocytic Lymphohistiocytosis." Journal of Microbiology and Infectious Diseases 12.2 (2022), 69-73 . Print. doi:10.5799/jmid.1130139



APA (American Psychological Association) Style

GARIMA Nirmal, Guruprasad Chellappan Sojamani, Manjusha Nair, Swapna R Nath, Priyakumari Thankamony (2022) Disseminated Fusariosis with Secondary Hemophagocytic Lymphohistiocytosis. Journal of Microbiology and Infectious Diseases, 12 (2), 69-73 . doi:10.5799/jmid.1130139