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2024, Vol: 14, Issue: 4
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Research Article 


In-vitro susceptibility of multiple drug resistant Pseudomonas aeruginosa to organic acids

Basavraj S Nagoba, Bharat Wadher, Sohan Selkar.


Cited By:3

Abstract
Objective: Pseudomonas aeruginosa is a classic opportunistic pathogen with innate resistance to many antibiotics and disinfectants. Resistance to antimicrobial agents makes it the most noxious organism to eliminate from infection site. In view of its antimicrobial resistance, an attempt was made to study its susceptibility to various organic acids.
Methods: Seven clinical isolates of P.aeruginosa resistant to multiple antibiotics were subjected to in vitro susceptibility to various organic acids by broth dilution method to find out susceptibility to various organic acids.
Results: The isolates of P.aeruginosa resistant to 14 antimicrobials were found susceptible to one percent oxalic acid and trichloroacetic acid, two percent lactic acid and citric acid, and three percent acetic acid. It is interesting to note that strains resistant to multiple antibiotics were also found susceptible to organic acids. Oxalic acid and trichloroacetic acid were found highly effective.
Conclusions: Clinical use of oxalic acid, trichloroacetic acid and lactic acid as topical agents to treat superficial pseu¬domonal infections caused by difficult strains of P.aeruginosa may be recommended after confirmation of their toxicity and in vivo efficacy in animal models. J Microbiol Infect Dis 2013; 3(2): 67-70

Key words: Pseudomonas aeruginosa, Multiple Antibiotic Resistance, Susceptibility to Organic Acids.


 
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How to Cite this Article
Pubmed Style

Nagoba BS, Wadher B, Selkar S. In-vitro susceptibility of multiple drug resistant Pseudomonas aeruginosa to organic acids. J Microbiol Infect Dis. 2013; 3(2): 67-70 . doi:10.5799/jmid2013.02.0083

Web Style

Nagoba BS, Wadher B, Selkar S. In-vitro susceptibility of multiple drug resistant Pseudomonas aeruginosa to organic acids. https://www.jmidonline.org/?mno=302656983 [Access: January 09, 2025]. doi:10.5799/jmid2013.02.0083

AMA (American Medical Association) Style

Nagoba BS, Wadher B, Selkar S. In-vitro susceptibility of multiple drug resistant Pseudomonas aeruginosa to organic acids. J Microbiol Infect Dis. 2013; 3(2): 67-70 . doi:10.5799/jmid2013.02.0083


Vancouver/ICMJE Style

Nagoba BS, Wadher B, Selkar S. In-vitro susceptibility of multiple drug resistant Pseudomonas aeruginosa to organic acids. J Microbiol Infect Dis. (2013), [cited January 09, 2025]; 3(2): 67-70 . doi:10.5799/jmid2013.02.0083


Harvard Style

Nagoba, B. S., Wadher, . B. & Selkar, . S. (2013) In-vitro susceptibility of multiple drug resistant Pseudomonas aeruginosa to organic acids. J Microbiol Infect Dis, 3 (2), 67-70 . doi:10.5799/jmid2013.02.0083


Turabian Style

Nagoba, Basavraj S, Bharat Wadher, and Sohan Selkar. 2013. In-vitro susceptibility of multiple drug resistant Pseudomonas aeruginosa to organic acids. Journal of Microbiology and Infectious Diseases, 3 (2), 67-70 . doi:10.5799/jmid2013.02.0083


Chicago Style

Nagoba, Basavraj S, Bharat Wadher, and Sohan Selkar. "In-vitro susceptibility of multiple drug resistant Pseudomonas aeruginosa to organic acids." Journal of Microbiology and Infectious Diseases 3 (2013), 67-70 . doi:10.5799/jmid2013.02.0083


MLA (The Modern Language Association) Style

Nagoba, Basavraj S, Bharat Wadher, and Sohan Selkar. "In-vitro susceptibility of multiple drug resistant Pseudomonas aeruginosa to organic acids." Journal of Microbiology and Infectious Diseases 3.2 (2013), 67-70 . Print. doi:10.5799/jmid2013.02.0083


APA (American Psychological Association) Style

Nagoba, B. S., Wadher, . B. & Selkar, . S. (2013) In-vitro susceptibility of multiple drug resistant Pseudomonas aeruginosa to organic acids. Journal of Microbiology and Infectious Diseases, 3 (2), 67-70 . doi:10.5799/jmid2013.02.0083


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Journal of Microbiology and Infectious Diseases

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