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Abstract - Evaluation of COVID-19 Patients with Chronic Kidney Disease
Yasaman Sadat Keshmiri, Sina Khosravi Mirzaei, Shahnaz Sali, Davood Yadegarynia, Sara Abolghasemi, Shabnam Tehrani, Amir Zamani, Mohamad Mehdi Derisi

Evaluation of COVID-19 Patients with Chronic Kidney Disease

Yasaman Sadat Keshmiri1, Sina Khosravi Mirzaei1, Shahnaz Sali2, Davood Yadegarynia2, Sara Abolghasemi2, Shabnam Tehrani2, Amir Zamani1, Mohamad Mehdi Derisi1

 

1School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran

2Infectious Diseases and Tropical Medicine Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran

 

ABSTRACT

Objectives: The present study seeks to provide insight into managing patients with chronic kidney disease (CKD) infected with COVID-19.

Methods: Patients with COVID-19 with CKD were included in the study. The eligible patients were divided into four groups: 1) patients who were not on dialysis, 2) patients on maintenance dialysis, 3) patients who underwent dialysis following COVID-19, 4) patients with a history of a kidney transplant. After reviewing clinical charts, nursing records, laboratory findings, radiological reports, and other medical records of CKD patients with COVID-19 confirmed infection, clinical presentation, laboratory data, radiology findings, and results were extracted from documented medical records. The epidemiological, clinical, laboratory and outcome characteristics of the subgroups were evaluated and compared.

Results: Seventy-eight patients were included into the study. Hypertension (50 cases, 72.5%), diabetes (44 cases, 63.8%), and Cardiovascular disease (26 cases, 38.2%) were the most common risk factors in the studied patients. Among all participants, 40 (52.6%) patients died. The most common symptom was dyspnea (56.6%), followed by dry cough (38.7%). Comparison of blood, inflammatory, biochemical, and clinical indices among the patients' groups show that LDH (P=0.022), AST (P=0.038), and ALT (P= 0.004) indices were significantly different between groups of patients. According to the results in Table 3, Unilateral ground-glass opacity (GGO) in the radiological findings of the Non-dialysis CKD group was significantly (P=0.50) higher than the other groups.

Conclusion: It can be concluded that CKD is one of the critical factors that can cause poor prognosis in COVID-19 patients.  J Microbiol Infect Dis 2021; 11(3):152-158.

Keywords: COVID19, chronic kidney disease, Dialysis, Transplant

 

Volume 11, Number 03 (2021)